Captain's Mode second pick phase is changed from Dire/Radiant/Dire/Radiant to Dire/Radiant/Radiant/Dire (assuming Radiant is first pick)
Multiple Critical Strike procs are now rolled from strongest to weakest and will stop rolling once a proc occurs (this results in the same DPS but is less lilkely to have multiple crits in a row or multiple attacks without a crit.)
Cooldown Percentage Reduction no longer stacks (Sources of flat cooldown reduction still stack)
Increased HP Regen of all heroes with 0 HP Regen to 0.25
Water Rune healing reduced from 80HP to 40HP
Second Roshan no longer drops cheese
Neutral Creeps now drop 5 neutral items per tier